CONFERENCES

Webinars and Meetings

CONFERENCES

Webinars and Meetings

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Webinars and Meetings

Due to the COVID-19 pandemic and safety issues related to holding in person meetings, we are instead organizing a series of webinars on specific topics.  The goal is to promote continued communication within the dysferlin research community so that scientists can stay current with the latest advances. Topics that we intend to cover include areas of research where we are seeing movement or breakthroughs that will help advance the field.

If you would like to view a recording of any of the webinars, please email us at admin@jain-foundation.org.

Upcoming Webinars and Meetings

Dysferlin Protein Structure and Interactions – July 21 & 22, 2021

All times EDT (UTC-4)

Wednesday, July 21

11:00 AM Introduction (Jain Foundation)

11:05 AM R. Bryan Sutton, Texas Tech University: “Redefining the Architecture of Dysferlin and its Implications in LGMD2B”

11:30 AM Colin Johnson and Joseph Baio, Oregon State University: “Combining NMR and nonlinear spectroscopy to get a molecular level view of dysferlin bound to lipids”

12:00 PM Lance Stewart, University of Washington: “Dysferlin Structure Prediction by Rosetta”

12:30 PM Discussion

Thursday, July 22

11:00 AM Introduction (Jain Foundation)

11:05 AM Dennis G. Drescher, Marian J. Drescher; Wayne State University : “Dysferlin protein-protein interactions with presumptive repair proteins”

11:30 AM Peter Fridy, Rockefeller University: “Nanobodies as Proteomic Tools for Dysferlin”

12:00 PM (Tentative) Kevin Sonnemann, University of Wisconsin, title TBA

12:30 PM Discussion

Link to webinar registration: https://us02web.zoom.us/webinar/register/WN_T-ctgOUwTe6e5Cfm7WG2Mw

Future Webinars

Dysferlin and Metabolism – TBA

Previous Webinars and Meetings

Session 1: Lipid accumulation and Fat replacement in vitro and in vivo

7:00 AM – 9:00 AM PDT (1400—1600 UTC) Tuesday, June 29, 2020

7:00 Jain Foundation–Session Introduction

7:10 Matthew Watt—University of Melbourne, Dysferlin Deficiency Alters Lipid Metabolism and Remodels the Skeletal Muscle Lipidome in Mice 

7:35 Alastair Khodabukus/Nenad Bursac—Duke University, A novel 3D tissue-engineered human iPSC model of dysferlin-deficient skeletal muscle – studies of contractile function and lipid response

7:50 Anil Agarwal–UT Southwestern, Insights into Lipid Accumulation in Skeletal Muscle

8:05 Pierre Carlier—Institute of Myology, Quantitative NMR Imaging Biomarkers for Disease Progression and Disease Activity in Skeletal Muscle of Dysferlinopathy Patients: Fat Fraction and Water T2

8:20 Questions and Discussion

Tuesday, June 30, 2020: Pathways: FAPs, Cholesterol, and Metabolism

7:00 Jain Foundation–Session Introduction

7:10 Jyoti Jaiswal–George Washington University and Children’s Research Institute, Misdirected Fate of a Multipotent Stem Cell Drives Disease Progress in LGMD2B

7:35 Lorenzo Puri–Sanford Burnham Prebys Medical Discovery Institute, Investigation of the Role of Fibro/Adipogenic Progenitors and the Effect of HDAC Inhibitors in Dysferlinopathy

7:50 Pascal Bernatchez—University of British Columbia, Is Muscle Wasting in Dysferlinopathies the Result of Whole-Body Lipoprotein Abnormalities? Lessons from Duchenne Muscular Dystrophy

8:15 Questions and Discussion

Webinar Summary

Wednesday, April 21

10:00 AM Introduction (Jain Foundation)

10:05 AM Miranda Grounds, University of Western Australia; Erin Lloyd, University of Western Australia; Robyn Murphy, Latrobe University: “Functional and Molecular parameters related to Ca handling, show different impact of dysferlin-deficiency on slow and fast muscles of BLAJ mice aged 10 months”

10:55 AM Nenad Bursac, Duke University: “Human myobundles: a novel platform to study dysferlinopathy mechanisms and treatment”

11:25 AM Discussion

Thursday, April 22

10:00 AM Introduction (Jain Foundation)

10:05 AM Bradley Launikonis, University of Queensland: “Ryanodine receptor leak and Ca2+ redistribution in dysferlinopathy”

10:45 AM Robert Bloch, University of Maryland: “Dysferlin Stabilizes Calcium Release at the Triad Junction”

11:15 AM Discussion

Webinar Summary